NASDAQ: SRPT

Sarepta Therapeutics (SRPT) Stock Analysis & Forecast

Oct 12 close

$17.44−0.41 (−2.3%)

Gekko Brief

AI summaryOct 12 close

This week brought several analyst actions alongside new clinical data on Sarepta Therapeutics' (SRPT) ELEVIDYS gene therapy. Bank of America Securities reaffirmed a Sell rating with an $18.00 price target, while RBC Capital cut its target to $17 from $19, keeping a Sector Perform, Speculative Risk rating. Separately, new two-year ELEVIDYS data in older Duchenne muscular dystrophy patients showed clinical benefits and a consistent safety profile, presented at the World Muscle Society congress and extending evidence to older patients while reinforcing protein expression in young children. Regenxbio and the University of Pennsylvania also settled a long-running gene-therapy patent dispute tied to Elevidys, dismissed with prejudice.

SRPT closed at $17.44, down 2.3%, sitting below both its 50-day average of $19.11 and 200-day average of $19.00. The stock has fallen 14.7% over one month and 20% over six months. The GekkoIndex reads 65.8, placing it in the Accumulation zone, down 0.7 over five days. Price sits 13.2% below Gekko Fair Value of $20.09.

Sarepta next reports earnings on 4 November 2026, after close, 23 days away and inside a typical 20-trading-day holding window; its last report showed EPS of $0.42 against an estimate of $0.34, with a 2.4% reaction, and it has beaten estimates in 4 of the last 8 quarters, with an average absolute reaction of 13%. No insider, Congress, or unusual options activity appears in the respective 90-day and 30-day windows. Seasonality from this point has averaged -10.8% over the next 20 trading days across 5 years, rising in 1 of them. Consensus among 16 firms includes 3 buy, 9 hold, and 4 sell ratings, with a consensus target of $21.64.

Written by AI from the Oct 12, 2026 close and checked automatically against the figures on this page.

Sarepta Therapeutics price vs fair value

$20.09$17.44Oct ’25Apr ’26Oct ’26
Close $17.44200-day averageGekko Fair Value $20.09

Sarepta Therapeutics quick facts

Market cap
$1.84B
P/E ratio
—
Forward P/E
19.2
EPS, TTM
−$1.57
Revenue, TTM
$1.97B
Profit margin
-6.9%
Dividend yield
—
Beta
0.38
Volume
3.28M avg 2.74M
1-year return
−24.6%
Typical daily move
±4.9%
Typical 20-day move
±9.6%
50-day average
$19.11
200-day average
$19.00
Next earnings
Nov 4 after close
Shares outstanding
105.6M
52-week range
$14.68$24.68

Sarepta Therapeutics swing-trade checklist

Sarepta Therapeutics scores 2 supportive, 1 mixed and 2 headwinds across the 5 checklist items with data.

Six things swing traders check before a 20-day hold, read from the latest data.

2 supportive1 mixed2 headwinds

  • Trendmixed

    Averages disagree

    Close $17.44 sits between the 50-day ($19.11) and 200-day ($19.00) averages, or the averages disagree.

    See the chart
  • GekkoIndexsupportive

    65.8, Accumulation

    Reading 65.8 is in the Accumulation zone.

    See the GekkoIndex
  • Fair valuesupportive

    13.2% below

    Price is 13.2% below Gekko Fair Value (more than 5% below).

    See fair value
  • Smart moneyno data

    No data

    No insider, Congress or unusual options activity in the window.

    See smart money
  • Earnings riskheadwind

    Reports in 23 days

    Reports on Nov 4, 2026, 23 days away — inside a typical 20-trading-day hold.

    See earnings
  • Seasonalityheadwind

    −10.8% on average

    From this point in the calendar, the next 20 trading days averaged −10.8% over 5 years, rising in 1 of them.

    See seasonality

A description of current data, not a recommendation. How this page works

Sarepta Therapeutics stock chart and price history

Sarepta Therapeutics closed at $17.44 on Oct 12, 2026, −24.6% over the past year, inside a 52-week range of $14.68 to $24.68.

Close50-day average200-day averageVolume
Sarepta Therapeutics share price, past year, with 50-day and 200-day moving averages and volume$30$40$50NovDecJan 2026FebMarAprMayJunJulAugSepOct17.44

Use the left and right arrow keys to read daily values.

Performance Breakdown

1 month
−14.7%
3 months
−2.9%
6 months
−20.0%
1 year
−24.6%
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About Sarepta Therapeutics

Sarepta Therapeutics develops genetic medicines for rare diseases, working with RNA-targeted therapeutics and gene therapies. It is known for treating Duchenne muscular dystrophy, with two approved products already on the market: EXONDYS 51 for patients whose dystrophin gene mutations respond to exon 51 skipping, and VYONDYS 53 for those with exon 53 skipping mutations.

Beyond these approved therapies, the company is advancing a pipeline that includes AMONDYS 45, built on exon-skipping chemistry targeting exon 45, and SRP-5051, a peptide-conjugated compound aimed at exon 51 of dystrophin pre-mRNA. It is also pursuing gene therapy candidates SRP-9001 for Duchenne muscular dystrophy and SRP-9003 for limb-girdle muscular dystrophies. This work is carried out partly through partnerships with outside institutions, among them F. Hoffman-La Roche, Nationwide Children's Hospital, Lysogene, Duke University, Genethon and StrideBio.

Sarepta Therapeutics was founded in 1980 and is headquartered in Cambridge, Massachusetts. Its shares are listed on the NASDAQ under the ticker SRPT.

Listed
NASDAQ
Sector
Health technology
Industry
Pharmaceuticals: major
Website
sarepta.com

Sarepta Therapeutics GekkoIndex: the smart money zone

Sarepta Therapeutics’s GekkoIndex — Gekko’s 0 to 100 smart money score — reads 65.8, in the Accumulation zone, down 0.7 points over five sessions.

010065.8Accumulation

Down 0.7 points over five sessions.

Reading for Oct 12, 2026

What followed past readings in each zone

ZoneReadings5 days10 days20 days50 days
Buying78+1.6%+3.6%+2.1%−11.5%
Accumulation (current zone)288−0.9%−1.3%−2.7%−10.7%
Neutral278−1.0%−2.9%−5.0%−6.9%
Distribution35−2.7%−3.6%−7.5%−6.3%
Selling3Too few readings yet

Average SRPT share-price change over the trading days after each daily reading in its GekkoIndex history. Across every stock Gekko tracks, Accumulation readings averaged +2.2% over 20 days. Past behaviour doesn’t guarantee future results.

Accumulation zone: Institutional interest building. About the five zones →

See every daily GekkoIndex reading plotted over the SRPT price, zone by zone.Track SRPT in Gekko

Is Sarepta Therapeutics stock overvalued? Gekko Fair Value

Sarepta Therapeutics trades 13.2% below Gekko Fair Value of $20.09, so the shares are undervalued on Gekko’s estimate.

Gekko’s own estimate of what Sarepta Therapeutics shares are worth, recalculated every trading day.

$20.09

Gekko Fair Value, Oct 10, 2026

13.2% Undervalued

At the end of Aug 2026 the price was 1.6% above the estimate.

Gekko Fair ValueShare price, month end
$20$18Aug 2026SepOct 2026

How Gekko Fair Value works →

Gekko Fair Value on every chart, with the gap to price updating daily.Open SRPT in Gekko

Sarepta Therapeutics insider and Congress trading

No open-market insider purchases were filed for Sarepta Therapeutics, and no Congress trades were disclosed, in the last 90 days.

Plus buybacks, unusual options and fund positions, each dated to when it became public.

Insider buying last 90 days

No open-market insider purchases were filed for SRPT in the last 90 days.

From Form 4 filings, dated to when each was filed.

Every SRPT insider filing, plotted on the chart in Gekko.Open SRPT in Gekko

Congress trades last 90 days

No trades in SRPT were disclosed by members of Congress in the last 90 days.

From congressional disclosures, which report amounts as ranges.

Congress disclosures for SRPT, plotted on the chart in Gekko.Open SRPT in Gekko

Buybacks

Sarepta Therapeutics has been buying back its own shares.

Bought back, year ended Dec 31, 2025
$25.01M
As a share of market cap
1.36%

From company filings.

Hedge funds and billionaires quarter ended Mar 31

0of the funds Gekko tracks hold SRPT.

0added0opened0trimmed2sold out
Which funds are on each side, name by name.Unlock in Gekko

Sarepta Therapeutics earnings: next date and track record

Sarepta Therapeutics reports on Nov 4, 2026, after the close (23 days away), and beat the EPS estimate in 4 of its last 8 reports.

4 of 8reports beat the EPS estimate
±13%average move across the report
2 of 8reports followed by a gain

Share-price move across each report

−3.7%Nov ’24−3.6%Feb ’25−42.3%May ’25+7.2%Aug ’25−32.5%Nov ’25−7.4%Feb ’26−4.5%May ’26+2.4%Aug ’26

Last earnings call, Aug 5, 2026 AI summary

What they said
Sarepta delivered GAAP and non-GAAP operating profitability in Q2 2026, with cash and investments increasing approximately $197 million during the quarter. The PMO franchise remained stable while ELEVIDYS performed in line with expectations with improving enrollment forms. Management highlighted their siRNA pipeline with promising preclinical and early clinical data in FSHD and DM1. The company has 4 approved Duchenne therapies and upcoming regulatory decisions for VVYONDYS and AMONDYS.
Guidance
Sarepta narrowed 2026 total net product revenue guidance to $1.2 billion to $1.3 billion, with the midpoint as the primary reference. Key upcoming milestones include Cohort 8 data and new siRNA program data in H2 2026.
ReportedEPSSurpriseRevenueSurpriseMove
Aug 5, 2026$0.42
est $0.34
+23.5%$401.3M
est $366.4M
+9.5%+2.4%
May 6, 2026$3.16
est $1.05
+201.0%$730.8M
est $474.2M
+54.1%−4.5%
Feb 25, 2026−$3.58
est −$1.05
−241.0%$442.9M
est $369.6M
+19.8%−7.4%
Nov 3, 2025−$0.13
est $0.01
−1,400.0%$399.4M
est $391.4M
+2.0%−32.5%
Aug 6, 2025$2.02
est $1.11
+82.0%$611.1M
est $342.9M
+78.2%+7.2%
May 6, 2025−$3.42
est −$0.65
−426.2%$744.9M
est $687.5M
+8.3%−42.3%
Feb 26, 2025$1.90
est $2.06
−7.8%$658.4M
est $631.0M
+4.3%−3.6%
Nov 6, 2024$0.34
est −$0.13
+361.5%$467.2M
est $407.2M
+14.7%−3.7%

“Move” is the close of the first session after the report compared with the close of the last session before it, so it reads the same whether the company reported before the open or after the close.

Sarepta Therapeutics stock forecast and analyst price targets

Analysts’ average 12-month price target for Sarepta Therapeutics is $21.64, +24.1% from the last close, from 16 firms rating the stock in the last 90 days.

$21.64consensus 12-month target, +24.1% from the last close
Low $5High $38
Buy3
Hold9
Sell4

Each firm’s latest rating in the last 90 days: 16 firms.

Latest analyst actions

DateFirmRatingTargetvs price
Oct 9Bank of America SecuritiesSell, reiterated$18+3.2%
Oct 9RBC CapitalHold, maintained$17−2.5%
Oct 8RBC CapitalHold, maintained$17−2.5%
Oct 5H.C. WainwrightSell, reiterated$5−71.3%
Sep 30J.P. MorganHold, reiterated$20+14.7%
−2.7%average 20-day move after past Accumulation readings
−10.8%average move over the next 20 trading days in the last 5 years
±4.9%typical daily move, from the 14-day average range

Gekko doesn’t publish price predictions. These are analyst targets and historical base rates, which don’t guarantee future results.

Sarepta Therapeutics seasonality: the next 20 trading days

Over the next 20 trading days from Oct 10, Sarepta Therapeutics averaged −10.8% across the last 5 years, rising in 1 of them.

Next 20 trading days, by year

−2.3%2021−7.6%2022−32.5%2023−1.6%2024−20.3%2025

Average move and hit rate

WindowAverageYears higher
Next 5 trading days−0.1%3 of 5
Next 10 trading days−1.1%3 of 5
Next 15 trading days−7.1%3 of 5
Next 20 trading days−10.8%1 of 5
Next 30 trading days−14.0%1 of 5

For scale, SRPT’s typical 20-trading-day move in either direction is about 9.6%.

Sarepta Therapeutics market cap and key statistics

Sarepta Therapeutics’s market cap is $1.84B and revenue of $1.97B over the last twelve months.

Valuation

Market cap
$1.84B
Forward P/E
19.2
EPS, TTM
−$1.57
Gekko Fair Value
$20.09

Trading

Volume
3.28M
Avg volume, 20 days
2.74M
52-week high
$24.68
52-week low
$14.68
Shares outstanding
105.6M

Financials

Revenue, TTM
$1.97B
Profit margin
-6.9%
Return on equity
-9.5%
Quarterly earnings growth, YoY
+2,664.0%

Risk and income

Beta
0.38
Typical daily move
±4.9%
Typical 20-day move
±9.6%

Sarepta Therapeutics stock news this week

Coverage of Sarepta Therapeutics this week reads negative: 3 positive, 2 neutral and 7 negative headlines.

News sentiment negative

Sarepta Therapeutics peers

Sarepta Therapeutics’s 6 largest industry peers by market value, with today’s move, GekkoIndex zone and gap to Gekko Fair Value.

StockTodayGekkoIndex zonevs Fair Value
LLYEli Lilly+0.1%Neutral14.7% above
JNJJohnson & Johnson+0.8%Neutral3.2% below
ABBVAbbVie+1.3%Distribution28.2% above
MRKMerck−0.2%Neutral8.0% below
AZNAstraZeneca−0.7%Accumulation41.7% below
PFEPfizer−0.1%Neutral8.0% below

A peer links to its own page where one exists.

In the Buying zone today

Reporting earnings this week

Popular on Gekko

Sarepta Therapeutics stock FAQ

What is Sarepta Therapeutics’s market cap?

Sarepta Therapeutics’s market cap is $1.84B at the Oct 12, 2026 close of $17.44, with 105.6M shares outstanding.

What is the Sarepta Therapeutics stock forecast?

The consensus analyst 12-month price target for Sarepta Therapeutics is $21.64, +24.1% from the last close. Of the 16 firms that rated the stock in the last 90 days, 3 rate it a buy, 9 a hold and 4 a sell. Gekko doesn’t publish price predictions of its own.

Is Sarepta Therapeutics stock overvalued or undervalued?

On Gekko’s estimate Sarepta Therapeutics is undervalued: the Oct 12, 2026 close of $17.44 is 13.2% below Gekko Fair Value of $20.09. Gekko Fair Value is recalculated every trading day, and a gap inside 5% either way counts as about fair value.

When does Sarepta Therapeutics report earnings next?

Sarepta Therapeutics is expected to report on Nov 4, 2026, after the market closes (23 days away). Analysts expect earnings of $0.11 per share on revenue of $352.8M. Sarepta Therapeutics beat the earnings estimate in 4 of its last 8 reports, moving 13% on average across the report.

What is Sarepta Therapeutics’s 52-week high and low?

Sarepta Therapeutics’s 52-week high is $24.68 and its 52-week low is $14.68; it closed at $17.44 on Oct 12, 2026, −24.6% over the past year. Over the last five years the shares peaked at $173.25 on Jun 21, 2024.

Is Sarepta Therapeutics stock a buy right now?

Gekko describes the data; it does not make buy or sell recommendations. On the swing-trade checklist, 2 of the 5 items with data read as supportive (gekkoindex and fair value), 1 as mixed (trend) and 2 as headwinds (earnings risk and seasonality). The checklist is a description of current data, not a recommendation.

How this page works

During US trading hours the price at the top of the page is a delayed quote, refreshed every 15 minutes; everything else is rebuilt after each US market close. The GekkoIndex, Gekko Fair Value and the checklist are Gekko’s own, and the Gekko Brief is written by AI from this page’s data and checked against it before it is published. How Gekko’s data works →

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