Insider buying last 90 days
No open-market insider purchases were filed for AZN in the last 90 days.
From Form 4 filings, dated to when each was filed.
Nov 4 close
This week AstraZeneca disclosed a roughly $10 billion offer for Rhythm Pharmaceuticals, a move that would expand its rare disease portfolio. RBC Capital Markets analyst Trung Huynh maintained an Outperform rating and raised his price target from $195.27 to $204.18 following the company's third-quarter results, which showed 9-month 2026 total revenue growth of 7% and core EPS growth of 14%, with oncology, rare disease, and R&I all posting double-digit growth. Separately, AstraZeneca terminated a Phase III trial for Ultomiris in delayed graft function due to a low probability of meeting its primary efficacy endpoint, and the company also outlined a $2 billion restructuring initiative through 2029.
AZN closed at $189.01, up 2.8%, sitting above both its 50-day average of $165.62 and 200-day average of $180.04, with one-month returns of 19.2% and three-month returns of 17.3%. The GekkoIndex reads 41.3, placing the stock in the Distribution zone, down 12.6 over five days. Gap to Gekko Fair Value of $286.96 stands at -34.1%.
The next earnings date falls on 9 February 2027, outside a typical 20-trading-day holding window; the last report on 30 October showed EPS of $2.79 against a $2.6 estimate, with a 7% reaction. One billionaire holder is noted, though no insider, Congress, or options activity appears in their respective windows. Seasonality over the next 20 trading days has averaged 0.6% across 5 years, rising in 3 of them. The consensus target stands at $206.66, implying 9.3% upside.
Written by AI from the Nov 4, 2026 close and checked automatically against the figures on this page.
AstraZeneca scores 3 supportive, 1 mixed and 1 headwind across the 5 checklist items with data.
Six things swing traders check before a 20-day hold, read from the latest data.
3 supportive1 mixed1 headwind
Averages disagree
Close $189.01 sits between the 50-day ($165.62) and 200-day ($180.04) averages, or the averages disagree.
See the chart41.3, Distribution
Reading 41.3 is in the Distribution zone.
See the GekkoIndex34.1% below
Price is 34.1% below Gekko Fair Value (more than 5% below).
See fair valueNo data
No insider, Congress or unusual options activity in the window.
See smart moneyReports in 96 days
Next report Feb 9, 2027, 96 days away — outside a typical 20-trading-day hold.
See earnings+0.6% on average
From this point in the calendar, the next 20 trading days averaged +0.6% over 5 years, rising in 3 of them.
See seasonalityA description of current data, not a recommendation. How this page works
AstraZeneca closed at $189.01 on Nov 4, 2026, +9.7% over the past year, inside a 52-week range of $153.41 to $212.71.
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Put AZN on a Gekko watchlist and see its GekkoIndex, Gekko Fair Value and smart money signals update on the chart as they change.
AstraZeneca is a biopharmaceutical company that takes medicines from early-stage research all the way to manufacturing and sale. Its drug lineup covers heart, kidney and metabolic disorders as well as cancer treatment, featuring names such as Tagrisso, Farxiga and Symbicort. The company also supplies products tied to COVID-19 and to rare medical conditions, among them Vaxzevria and Soliris.
Sales reach both general practitioners and specialists, carried out through teams of representatives and local offices spread across Britain, mainland Europe, the Americas, Asia, Africa and Australasia. Beyond its own labs, AstraZeneca teams up with outside groups on new science, working alongside Neurimmune on an antibody treatment, BenevolentAI on lupus research, Lunit on AI tools for reading lung cancer scans, and Absci on machine-learning methods for spotting oncology drug targets.
The business dates back to 1992, when it was formed as Zeneca Group PLC, before adopting the AstraZeneca name in April 1999. It runs its operations from Cambridge in the United Kingdom, and its stock trades on the NYSE under the ticker AZN.
AstraZeneca’s GekkoIndex — Gekko’s 0 to 100 smart money score — reads 41.3, in the Distribution zone, down 12.6 points over five sessions.
Down 12.6 points over five sessions, from the Neutral zone.
Reading for Nov 4, 2026
| Zone | Readings | 5 days | 20 days | ||
|---|---|---|---|---|---|
| Buying | 25 | +1.3% | +3.2% | ||
| Accumulation | 171 | +0.7% | +0.8% | ||
| Neutral | 353 | +0.1% | +1.2% | ||
| Distribution (current zone) | 11 | −1.3% | +2.2% | ||
| Selling | 2 | Too few readings yet | |||
Average AZN share-price change over the trading days after each daily reading in its GekkoIndex history. Across every stock Gekko tracks, Distribution readings averaged +1.2% over 20 days. Past behaviour doesn’t guarantee future results.
Distribution zone: Institutions potentially offloading. About the five zones →
AstraZeneca trades 34.1% below Gekko Fair Value of $286.96, so the shares are undervalued on Gekko’s estimate.
Gekko’s own estimate of what AstraZeneca shares are worth, recalculated every trading day.
$286.96
Gekko Fair Value, Nov 4, 2026
34.1% Undervalued
At the end of Sep 2026 the price was 40.1% below the estimate.
No open-market insider purchases were filed for AstraZeneca, and no Congress trades were disclosed, in the last 90 days.
Plus buybacks, unusual options and fund positions, each dated to when it became public.
No open-market insider purchases were filed for AZN in the last 90 days.
From Form 4 filings, dated to when each was filed.
No trades in AZN were disclosed by members of Congress in the last 90 days.
From congressional disclosures, which report amounts as ranges.
AstraZeneca has been buying back its own shares.
From company filings.
1of the funds Gekko tracks holds AZN.
AstraZeneca reports on Feb 9, 2027, before the open (96 days away), and beat the EPS estimate in 7 of its last 8 reports.
Feb 9, 2027
Expected before the open, 96 days away
| Reported | EPS | Revenue | Move |
|---|---|---|---|
| Oct 30, 2026 | $2.79 est $2.60 | $16.21B est $16.00B | +7.0% |
| Jul 27, 2026 | $2.63 est $2.50 | $15.38B est $15.44B | +1.9% |
| Apr 29, 2026 | $1.29 est $1.27 | $15.29B est $14.93B | +0.4% |
| Feb 10, 2026 | $2.12 est $2.09 | $15.50B est $15.44B | +8.9% |
| Nov 6, 2025 | $2.38 est $2.28 | $15.19B est $14.78B | +0.6% |
| Jul 29, 2025 | $2.18 est $2.18 | $14.46B est $14.10B | +6.0% |
| Apr 29, 2025 | $2.48 est $2.20 | $13.59B est $13.81B | +5.0% |
| Feb 6, 2025 | $2.10 est $2.07 | $14.89B est $14.23B | +6.1% |
“Move” is the close of the first session after the report compared with the close of the last session before it, so it reads the same whether the company reported before the open or after the close.
Analysts’ average 12-month price target for AstraZeneca is $206.66, +9.3% from the last close.
Gekko doesn’t publish price predictions. These are analyst targets and historical base rates, which don’t guarantee future results.
Over the next 20 trading days from Nov 4, AstraZeneca averaged +0.6% across the last 5 years, rising in 3 of them.
| Window | Average | Years higher |
|---|---|---|
| Next 5 trading days | −1.1% | 2 of 5 |
| Next 10 trading days | −2.0% | 3 of 5 |
| Next 15 trading days | +0.2% | 3 of 5 |
| Next 20 trading days | +0.6% | 3 of 5 |
| Next 30 trading days | +0.5% | 3 of 5 |
For scale, AZN’s typical 20-trading-day move in either direction is about 4.8%.
AstraZeneca’s market cap is $293.1B, with a P/E ratio of 26.4 and revenue of $62.38B over the last twelve months.
Coverage of AstraZeneca this week reads positive: 4 positive, 2 neutral and 1 negative headlines.
AstraZeneca’s 6 largest industry peers by market value, with today’s move, GekkoIndex zone and gap to Gekko Fair Value.
| Stock | GekkoIndex zone | vs Fair Value |
|---|---|---|
| LLYEli Lilly | Distribution | 27.7% above |
| JNJJohnson & Johnson | Neutral | 1.7% below |
| ABBVAbbVie | Neutral | 26.5% above |
| MRKMerck | Neutral | 8.6% below |
| PFEPfizer | Neutral | 4.1% below |
| VRTXVertex Pharmaceuticals | Neutral | 16.8% above |
A peer links to its own page where one exists.
AstraZeneca’s market cap is $293.1B at the Nov 4, 2026 close of $189.01, with 1.55B shares outstanding. The shares trade on a P/E ratio of 26.4.
The consensus analyst 12-month price target for AstraZeneca is $206.66, +9.3% from the last close. Gekko doesn’t publish price predictions of its own.
On Gekko’s estimate AstraZeneca is undervalued: the Nov 4, 2026 close of $189.01 is 34.1% below Gekko Fair Value of $286.96. Gekko Fair Value is recalculated every trading day, and a gap inside 5% either way counts as about fair value.
AstraZeneca is expected to report on Feb 9, 2027, before the market opens (96 days away). Analysts expect earnings of $2.31 per share on revenue of $16.59B. AstraZeneca beat the earnings estimate in 7 of its last 8 reports, moving 4.5% on average across the report.
AstraZeneca’s 52-week high is $212.71 and its 52-week low is $153.41; it closed at $189.01 on Nov 4, 2026, +9.7% over the past year.
Gekko describes the data; it does not make buy or sell recommendations. On the swing-trade checklist, 3 of the 5 items with data read as supportive (fair value, earnings risk and seasonality), 1 as mixed (trend) and 1 as a headwind (gekkoindex). The checklist is a description of current data, not a recommendation.
During US trading hours the price at the top of the page is a delayed quote, refreshed every 15 minutes; everything else is rebuilt after each US market close. The GekkoIndex, Gekko Fair Value and the checklist are Gekko’s own, and the Gekko Brief is written by AI from this page’s data and checked against it before it is published. How Gekko’s data works →
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