NASDAQ: MDGL

Madrigal Pharmaceuticals (MDGL) Stock Analysis & Forecast

Sep 28 close

$517.04+0.48 (+0.1%)

Gekko Brief

AI summary

This week's attention on Madrigal Pharmaceuticals centers on a wave of analyst coverage. Goldman Sachs initiated coverage with a Buy rating and a $704.00 price target on 24 September, followed by a separate note reiterating that target on 25 September, with commentary describing the stock as undervalued. Citigroup also initiated coverage with a Buy rating and a $725 price target, noting its figure sits above the broader analyst consensus target of $678.18, which itself carries a consensus Buy rating.

MDGL closed at $517.04, essentially flat on the day, with its 50-day average at $526.27 and 200-day average at $511.83, placing the trend between the two. The GekkoIndex reads 62.2, in the Accumulation zone. Price sits 45.6% below Gekko Fair Value of $949.72. Over the past year the stock has returned 22.2%, though the past month shows a 4.9% decline, and shares trade well off their 52-week high of $615.00.

Looking ahead, Madrigal's next earnings report is set for 3 November, 35 days out and beyond a typical 20-trading-day holding window; its last report on 30 July beat estimates but the stock reacted with a 14.5% decline. Analyst sentiment remains heavily tilted toward Buy, with 13 of 14 firms rating it so and a consensus upside of 31.9%. Seasonality over this stretch has historically leaned negative, averaging -2.8% over 5 years with gains in only 1 of them. No insider, Congress, or unusual options activity appears in current windows.

Written by AI and checked automatically against the figures on this page. Generated Sep 29, 2026 from the data above.

Madrigal Pharmaceuticals price vs fair value

▲$949.72$517.04Sep ’25Mar ’26Sep ’26
Close $517.04200-day averageGekko Fair Value $949.72

Madrigal Pharmaceuticals quick facts

Market cap
$11.95B
P/E ratio
—
Forward P/E
78.1
EPS, TTM
−$14.01
Revenue, TTM
$1.28B
Profit margin
-25.3%
Dividend yield
—
Beta
-0.99
Volume
333,653 avg 219,500
1-year return
+22.2%
Typical daily move
±3.4%
Typical 20-day move
±9%
50-day average
$526.27
200-day average
$511.83
Next earnings
Nov 3 before open
Shares outstanding
23.10M
52-week range
$393.61$615.00

Madrigal Pharmaceuticals swing-trade checklist

Madrigal Pharmaceuticals scores 3 supportive, 1 mixed and 1 headwind across the 5 checklist items with data.

Six things swing traders check before a 20-day hold, read from the latest data.

3 supportive1 mixed1 headwind

  • Trendmixed

    Averages disagree

    Close $517.04 sits between the 50-day ($526.27) and 200-day ($511.83) averages, or the averages disagree.

    See the chart
  • GekkoIndexsupportive

    62.2, Accumulation

    Reading 62.2 is in the Accumulation zone.

    See the GekkoIndex
  • Fair valuesupportive

    45.6% below

    Price is 45.6% below Gekko Fair Value (more than 5% below).

    See fair value
  • Smart moneyno data

    No data

    No insider, Congress or unusual options activity in the window.

    See smart money
  • Earnings risksupportive

    Reports in 35 days

    Next report Nov 3, 2026, 35 days away — outside a typical 20-trading-day hold.

    See earnings
  • Seasonalityheadwind

    −2.8% on average

    From this point in the calendar, the next 20 trading days averaged −2.8% over 5 years, rising in 1 of them.

    See seasonality

A description of current data, not a recommendation. How this page works

Madrigal Pharmaceuticals stock chart and price history

Madrigal Pharmaceuticals closed at $517.04 on Sep 28, 2026, +22.2% over the past year, inside a 52-week range of $393.61 to $615.00.

Close50-day average200-day averageVolume
Madrigal Pharmaceuticals share price, past year, with 50-day and 200-day moving averages and volume$400$600NovDecJan 2026FebMarAprMayJunJulAugSep517.04

Use the left and right arrow keys to read daily values.

Performance Breakdown

1 month
−4.9%
3 months
−1.9%
6 months
+1.2%
1 year
+22.2%
The full MDGL chart adds GekkoIndex, insider, options, Congress and hedge fund markers, plus TrendCandles™.Open MDGL in Gekko

Follow Madrigal Pharmaceuticals through every session

Put MDGL on a Gekko watchlist and see its GekkoIndex, Gekko Fair Value and smart money signals update on the chart as they change.

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About Madrigal Pharmaceuticals

Madrigal Pharmaceuticals works on new medicines for conditions tied to the heart, metabolism, and liver, with a focus on drugs still moving through clinical testing rather than products already on the market. Its furthest-along candidate, resmetirom, targets the liver and works on a specific thyroid hormone receptor, and it is being studied in late-stage Phase III trials for treating non-alcoholic steatohepatitis, a liver disease often referred to as NASH.

Behind resmetirom sits a second compound, MGL-3745, kept in reserve in case it is needed to support or replace the lead candidate. Madrigal also has a partnership with Hoffmann-La Roche that spans research, development, and eventual commercialization work, linking its drug programs to a larger collaborator as they progress.

The company operates out of West Conshohocken, Pennsylvania, and its shares are listed on the NASDAQ under the ticker MDGL.

Listed
NASDAQ
Sector
Health technology
Industry
Pharmaceuticals: major
Website
madrigalpharma.com

Madrigal Pharmaceuticals GekkoIndex: the smart money zone

Madrigal Pharmaceuticals’s GekkoIndex — Gekko’s 0 to 100 smart money score — reads 62.2, in the Accumulation zone, up 2.1 points over five sessions.

010062.2Accumulation

Up 2.1 points over five sessions.

Reading for Sep 28, 2026

What followed past readings in each zone

ZoneReadings5 days10 days20 days50 days
Buying39+3.2%+4.4%+10.1%+20.6%
Accumulation (current zone)223+1.2%+3.3%+7.8%+17.3%
Neutral356+0.3%+0.4%+0.6%+2.9%
Distribution48+2.3%+3.8%+4.4%+0.3%
Selling6Too few readings yet

Average MDGL share-price change over the trading days after each daily reading in its GekkoIndex history. Across every stock Gekko tracks, Accumulation readings averaged +2.3% over 20 days. Past behaviour doesn’t guarantee future results.

Accumulation zone: Institutional interest building. About the five zones →

See every daily GekkoIndex reading plotted over the MDGL price, zone by zone.Track MDGL in Gekko

Is Madrigal Pharmaceuticals stock overvalued? Gekko Fair Value

Madrigal Pharmaceuticals trades 45.6% below Gekko Fair Value of $949.72, so the shares are undervalued on Gekko’s estimate.

Gekko’s own estimate of what Madrigal Pharmaceuticals shares are worth, recalculated every trading day.

$949.72

Gekko Fair Value, Sep 26, 2026

45.6% Undervalued

How Gekko Fair Value works →

Gekko Fair Value on every chart, with the gap to price updating daily.Open MDGL in Gekko

Madrigal Pharmaceuticals insider and Congress trading

No open-market insider purchases were filed for Madrigal Pharmaceuticals, and no Congress trades were disclosed, in the last 90 days.

Plus buybacks, unusual options and fund positions, each dated to when it became public.

Insider buying last 90 days

No open-market insider purchases were filed for MDGL in the last 90 days.

From Form 4 filings, dated to when each was filed.

Every MDGL insider filing, plotted on the chart in Gekko.Open MDGL in Gekko

Congress trades last 90 days

No trades in MDGL were disclosed by members of Congress in the last 90 days.

From congressional disclosures, which report amounts as ranges.

Congress disclosures for MDGL, plotted on the chart in Gekko.Open MDGL in Gekko

Hedge funds and billionaires quarter ended Jun 30

1of the funds Gekko tracks holds MDGL.

0added0opened1trimmed1sold out
Which funds are on each side, name by name.Unlock in Gekko

Madrigal Pharmaceuticals earnings: next date and track record

Madrigal Pharmaceuticals reports on Nov 3, 2026, before the open (35 days away), and beat the EPS estimate in 6 of its last 8 reports.

6 of 8reports beat the EPS estimate
±14.8%average move across the report
5 of 8reports followed by a gain

Share-price move across each report

+48.0%Oct ’24+8.5%Feb ’25−5.5%May ’25+8.3%Aug ’25+15.4%Nov ’25−11.5%Feb ’26+6.4%May ’26−14.5%Jul ’26
ReportedEPSSurpriseRevenueSurpriseMove
Jul 30, 2026−$1.99
est −$2.55
+22.0%$364.3M
est $352.1M
+3.5%−14.5%
May 6, 2026−$1.38
est −$4.14
+66.7%$311.3M
est $301.1M
+3.4%+6.4%
Feb 19, 2026−$2.57
est $0.04
−6,525.0%$321.1M
est $312.5M
+2.8%−11.5%
Nov 4, 2025−$4.96
est −$1.99
−149.2%$287.3M
est $245.0M
+17.3%+15.4%
Aug 5, 2025−$1.90
est −$3.48
+45.4%$212.8M
est $243.5M
−12.6%+8.3%
May 1, 2025−$3.32
est −$3.79
+12.4%$137.3M
est $158.9M
−13.6%−5.5%
Feb 26, 2025−$2.71
est −$4.12
+34.3%$103.3M
est $97.81M
+5.6%+8.5%
Oct 31, 2024−$4.92
est −$6.91
+28.8%$62.18M
est $92.53M
−32.8%+48.0%

“Move” is the close of the first session after the report compared with the close of the last session before it, so it reads the same whether the company reported before the open or after the close.

Madrigal Pharmaceuticals stock forecast and analyst price targets

Analysts’ average 12-month price target for Madrigal Pharmaceuticals is $682.11, +31.9% from the last close, from 14 firms rating the stock in the last 90 days.

$682.11consensus 12-month target, +31.9% from the last close
Low $543High $962
Buy13
Hold1
Sell0

Each firm’s latest rating in the last 90 days: 14 firms.

Latest analyst actions

DateFirmRatingTargetvs price
Sep 24Goldman SachsBuy, initiated$704+36.2%
Sep 23CitiBuy, initiated$725+40.2%
Aug 4Wolfe ResearchBuy, upgraded$605+17.0%
Aug 3BarclaysBuy, maintained$962+86.1%
Jul 31B. Riley SecuritiesBuy, initiated$670+29.6%
+7.8%average 20-day move after past Accumulation readings
−2.8%average move over the next 20 trading days in the last 5 years
±3.4%typical daily move, from the 14-day average range

Gekko doesn’t publish price predictions. These are analyst targets and historical base rates, which don’t guarantee future results.

Madrigal Pharmaceuticals seasonality: the next 20 trading days

Over the next 20 trading days from Sep 29, Madrigal Pharmaceuticals averaged −2.8% across the last 5 years, rising in 1 of them.

Next 20 trading days, by year

−7.2%2021+13.0%2022−17.6%2023+2.3%2024−1.7%2025

Average move and hit rate

WindowAverageYears higher
Next 5 trading days+2.3%1 of 5
Next 10 trading days+0.2%3 of 5
Next 15 trading days−1.3%2 of 5
Next 20 trading days−2.8%1 of 5
Next 30 trading days+19.0%4 of 5

For scale, MDGL’s typical 20-trading-day move in either direction is about 9%.

Madrigal Pharmaceuticals market cap and key statistics

Madrigal Pharmaceuticals’s market cap is $11.95B and revenue of $1.28B over the last twelve months.

Valuation

Market cap
$11.95B
Forward P/E
78.1
EPS, TTM
−$14.01
Gekko Fair Value
$949.72

Trading

Volume
333,653
Avg volume, 20 days
219,500
52-week high
$615.00
52-week low
$393.61
Shares outstanding
23.10M

Financials

Revenue, TTM
$1.28B
Profit margin
-25.3%
Return on equity
-53.3%
Quarterly earnings growth, YoY
0.0%

Risk and income

Beta
-0.99
Typical daily move
±3.4%
Typical 20-day move
±9%

Madrigal Pharmaceuticals stock news this week

Coverage of Madrigal Pharmaceuticals this week reads positive: 3 positive, 0 neutral and 0 negative headlines.

News sentiment positive

Madrigal Pharmaceuticals peers

Madrigal Pharmaceuticals’s 6 largest industry peers by market value, with today’s move, GekkoIndex zone and gap to Gekko Fair Value.

StockTodayGekkoIndex zonevs Fair Value
LLYEli Lilly+0.4%Neutral17.9% above
JNJJohnson & Johnson+0.7%Neutral0.5% above
ABBVAbbVie+0.7%Neutral23.3% above
MRKMerck+0.7%Neutral4.2% below
AZNAstraZeneca+0.3%Neutral39.9% below
PFEPfizer+0.4%Neutral4.0% below

A peer links to its own page where one exists.

In the Buying zone today

Reporting earnings this week

Popular on Gekko

Madrigal Pharmaceuticals stock FAQ

What is Madrigal Pharmaceuticals’s market cap?

Madrigal Pharmaceuticals’s market cap is $11.95B at the Sep 28, 2026 close of $517.04, with 23.10M shares outstanding.

What is the Madrigal Pharmaceuticals stock forecast?

The consensus analyst 12-month price target for Madrigal Pharmaceuticals is $682.11, +31.9% from the last close. Of the 14 firms that rated the stock in the last 90 days, 13 rate it a buy, 1 a hold and 0 a sell. Gekko doesn’t publish price predictions of its own.

Is Madrigal Pharmaceuticals stock overvalued or undervalued?

On Gekko’s estimate Madrigal Pharmaceuticals is undervalued: the Sep 28, 2026 close of $517.04 is 45.6% below Gekko Fair Value of $949.72. Gekko Fair Value is recalculated every trading day, and a gap inside 5% either way counts as about fair value.

When does Madrigal Pharmaceuticals report earnings next?

Madrigal Pharmaceuticals is expected to report on Nov 3, 2026, before the market opens (35 days away). Analysts expect earnings of −$1.00 per share on revenue of $404.7M. Madrigal Pharmaceuticals beat the earnings estimate in 6 of its last 8 reports, moving 14.8% on average across the report.

What is Madrigal Pharmaceuticals’s 52-week high and low?

Madrigal Pharmaceuticals’s 52-week high is $615.00 and its 52-week low is $393.61; it closed at $517.04 on Sep 28, 2026, +22.2% over the past year.

Is Madrigal Pharmaceuticals stock a buy right now?

Gekko describes the data; it does not make buy or sell recommendations. On the swing-trade checklist, 3 of the 5 items with data read as supportive (gekkoindex, fair value and earnings risk), 1 as mixed (trend) and 1 as a headwind (seasonality). The checklist is a description of current data, not a recommendation.

How this page works

During US trading hours the price at the top of the page is a delayed quote, refreshed every 15 minutes; everything else is rebuilt after each US market close. The GekkoIndex, Gekko Fair Value and the checklist are Gekko’s own, and the Gekko Brief is written by AI from this page’s data and checked against it before it is published. How Gekko’s data works →

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