NASDAQ: ANAB

AnaptysBio (ANAB) Stock Analysis & Forecast

Oct 12 close

$46.04+0.09 (+0.2%)

Gekko Brief

Oct 12 close

AnaptysBio closed at $46.04 on 12 October 2026, +0.2% on the day. The price sits below both the 50-day ($54.19) and 200-day ($54.42) moving averages, inside a 52-week range of $30.27 to $72.36. The GekkoIndex reads 70.8, in the Buying zone, up 0.8 points over five sessions. Gekko Fair Value is $66.63, so the price is 30.9% below it.

The next earnings report is due on 3 November 2026, 22 days away (after close). Over the last 8 reports the company beat the earnings estimate 6 times, with an average move of 5.5% across the report. Seasonally, the next 20 trading days from this point averaged +5.2% over the last 5 years, rising in 3 of them.

7 firms rate the stock: 7 buy, 0 hold and 0 sell, with a consensus target of $87.25. A typical daily move is about 4.4%, and a typical 20-day move about 11.1%. On the swing-trade checklist, 3 items read supportive and 2 read as a headwind (trend, earnings risk).

A plain summary of the figures as of the Oct 12, 2026 close.

AnaptysBio price vs fair value

$66.63$46.04Oct ’25Apr ’26Oct ’26
Close $46.04200-day averageGekko Fair Value $66.63

AnaptysBio quick facts

Market cap
$1.36B
P/E ratio
—
Forward P/E
21
EPS, TTM
−$0.96
Revenue, TTM
$106.1M
Profit margin
247%
Dividend yield
—
Beta
0.45
Volume
371,592 avg 592,633
1-year return
+44.9%
Typical daily move
±4.4%
Typical 20-day move
±11.1%
50-day average
$54.19
200-day average
$54.42
Next earnings
Nov 3 after close
Shares outstanding
29.90M
52-week range
$30.27$72.36

AnaptysBio swing-trade checklist

AnaptysBio scores 3 supportive, 0 mixed and 2 headwinds across the 5 checklist items with data.

Six things swing traders check before a 20-day hold, read from the latest data.

3 supportive0 mixed2 headwinds

  • Trendheadwind

    Below 50 and 200-day

    Close $46.04 is below the 50-day ($54.19) and 200-day ($54.42) averages, and the 50-day is below the 200-day.

    See the chart
  • GekkoIndexsupportive

    70.8, Buying

    Reading 70.8 is in the Buying zone.

    See the GekkoIndex
  • Fair valuesupportive

    30.9% below

    Price is 30.9% below Gekko Fair Value (more than 5% below).

    See fair value
  • Smart moneyno data

    No data

    No insider, Congress or unusual options activity in the window.

    See smart money
  • Earnings riskheadwind

    Reports in 22 days

    Reports on Nov 3, 2026, 22 days away — inside a typical 20-trading-day hold.

    See earnings
  • Seasonalitysupportive

    +5.2% on average

    From this point in the calendar, the next 20 trading days averaged +5.2% over 5 years, rising in 3 of them.

    See seasonality

A description of current data, not a recommendation. How this page works

AnaptysBio stock chart and price history

AnaptysBio closed at $46.04 on Oct 12, 2026, +44.9% over the past year, inside a 52-week range of $30.27 to $72.36.

Close50-day average200-day averageVolume
AnaptysBio share price, past year, with 50-day and 200-day moving averages and volume$20$30$40$50$60$70NovDecJan 2026FebMarAprMayJunJulAugSepOct46.04

Use the left and right arrow keys to read daily values.

Performance Breakdown

1 month
−14.5%
3 months
−26.3%
6 months
+0.5%
1 year
+44.9%
The full ANAB chart adds GekkoIndex, insider, options, Congress and hedge fund markers, plus TrendCandles™.Open ANAB in Gekko

Follow AnaptysBio through every session

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About AnaptysBio

AnaptysBio develops antibody-based therapeutics aimed at autoimmune and inflammatory conditions within the United States. Its pipeline includes rosnilimab, which has completed a Phase 2b trial for moderate-to-severe rheumatoid arthritis by depleting pathogenic T cells, alongside ANB033, a CD122 antagonist being tested in Phase 1b for celiac disease and eosinophilic esophagitis. Other candidates include ANB101, an antibody in Phase 1a that targets plasmacytoid dendritic cells to limit interferon secretion, dostarlimab, a PD-1 antagonist studied across solid tumor types, and imsidolimab, which blocks the interleukin-36 receptor and is in Phase 3 testing for generalized pustular psoriasis.

The company advances many of its antibody programs toward preclinical and clinical milestones through partnerships, holding collaboration agreements with GSK and Vanda.

AnaptysBio is based in San Diego, California, and was incorporated in 2005 under the name Anaptys Biosciences, Inc. before adopting its current name in July 2006. Its shares are listed on the NASDAQ under the ticker ANAB.

Listed
NASDAQ
Sector
Health technology
Industry
Biotechnology
Website
anaptysbio.com

AnaptysBio GekkoIndex: the smart money zone

AnaptysBio’s GekkoIndex — Gekko’s 0 to 100 smart money score — reads 70.8, in the Buying zone, up 0.8 points over five sessions.

010070.8Buying

Up 0.8 points over five sessions.

Reading for Oct 12, 2026

What followed past readings in each zone

ZoneReadings5 days10 days20 days50 days
Buying (current zone)67+2.8%+7.7%+14.0%+26.3%
Accumulation115+2.3%+5.4%+8.2%+10.1%
Neutral357+0.9%+1.4%+3.6%+10.0%
Distribution46−1.6%−2.5%−2.6%+8.3%
Selling10+4.5%+3.5%+6.3%+16.5%

Average ANAB share-price change over the trading days after each daily reading in its GekkoIndex history. Across every stock Gekko tracks, Buying readings averaged +3.1% over 20 days. Past behaviour doesn’t guarantee future results.

Buying zone: Smart money likely accumulating heavily. About the five zones →

See every daily GekkoIndex reading plotted over the ANAB price, zone by zone.Track ANAB in Gekko

Is AnaptysBio stock overvalued? Gekko Fair Value

AnaptysBio trades 30.9% below Gekko Fair Value of $66.63, so the shares are undervalued on Gekko’s estimate.

Gekko’s own estimate of what AnaptysBio shares are worth, recalculated every trading day.

$66.63

Gekko Fair Value, Oct 10, 2026

30.9% Undervalued

At the end of Aug 2026 the price was 25.7% below the estimate.

Gekko Fair ValueShare price, month end
$67$46Aug 2026SepOct 2026

How Gekko Fair Value works →

Gekko Fair Value on every chart, with the gap to price updating daily.Open ANAB in Gekko

AnaptysBio insider and Congress trading

No open-market insider purchases were filed for AnaptysBio, and no Congress trades were disclosed, in the last 90 days.

Plus buybacks, unusual options and fund positions, each dated to when it became public.

Insider buying last 90 days

No open-market insider purchases were filed for ANAB in the last 90 days.

From Form 4 filings, dated to when each was filed.

Every ANAB insider filing, plotted on the chart in Gekko.Open ANAB in Gekko

Congress trades last 90 days

No trades in ANAB were disclosed by members of Congress in the last 90 days.

From congressional disclosures, which report amounts as ranges.

Congress disclosures for ANAB, plotted on the chart in Gekko.Open ANAB in Gekko

Buybacks

AnaptysBio has been buying back its own shares.

Latest authorization
$100.0M, Mar 27, 2026
Bought back, quarter ended Dec 31, 2025
$3.38M
As a share of market cap
0.25%
Trailing four quarters
$68.63M

From company filings.

Hedge funds and billionaires quarter ended Jun 30

3of the funds Gekko tracks hold ANAB.

1added2opened0trimmed0sold out
Which funds are on each side, name by name.Unlock in Gekko

AnaptysBio earnings: next date and track record

AnaptysBio reports on Nov 3, 2026, after the close (22 days away), and beat the EPS estimate in 6 of its last 8 reports.

6 of 8reports beat the EPS estimate
±5.5%average move across the report
2 of 8reports followed by a gain

Share-price move across each report

+11.4%Nov ’24−1.1%Feb ’25−5.0%May ’25−6.7%Aug ’25−0.1%Nov ’25+10.3%Mar ’26−7.7%May ’26−1.9%Sep ’26
ReportedEPSSurpriseRevenueSurpriseMove
Sep 11, 2026−$0.46
est −$0.46
0.0%$13.34M
est $14.06M
−5.1%−1.9%
May 12, 2026−$1.84
est −$1.07
−72.3%$25.56M
est $18.86M
+35.5%−7.7%
Mar 3, 2026$1.58
est $0.93
+69.9%$108.2M
est $87.04M
+24.4%+10.3%
Nov 4, 2025$0.52
est −$1.06
+149.1%$76.32M
est $87.09M
−12.4%−0.1%
Aug 7, 2025−$1.34
est −$1.50
+10.7%$22.26M
est $11.68M
+90.5%−6.7%
May 5, 2025−$1.28
est −$1.30
+1.5%$27.77M
est $15.27M
+81.8%−5.0%
Feb 27, 2025−$0.72
est −$1.55
+53.5%$43.11M
est $7.78M
+453.9%−1.1%
Nov 5, 2024−$1.14
est −$1.65
+30.9%$30.02M
est $8.21M
+265.8%+11.4%

“Move” is the close of the first session after the report compared with the close of the last session before it, so it reads the same whether the company reported before the open or after the close.

AnaptysBio stock forecast and analyst price targets

Analysts’ average 12-month price target for AnaptysBio is $87.25, +89.5% from the last close, from 7 firms rating the stock in the last 90 days.

$87.25consensus 12-month target, +89.5% from the last close
Low $60High $95
Buy7
Hold0
Sell0

Each firm’s latest rating in the last 90 days: 7 firms.

Latest analyst actions

DateFirmRatingTargetvs price
Oct 5H.C. WainwrightBuy, reiterated$95+106.3%
Sep 30J.P. MorganBuy, reiterated$60+30.3%
Sep 23Leerink PartnersBuy, maintained$81+75.9%
Sep 22H.C. WainwrightBuy, reiterated$95+106.3%
Sep 22BarclaysBuy, maintained$75+62.9%
+14.0%average 20-day move after past Buying readings
+5.2%average move over the next 20 trading days in the last 5 years
±4.4%typical daily move, from the 14-day average range

Gekko doesn’t publish price predictions. These are analyst targets and historical base rates, which don’t guarantee future results.

AnaptysBio seasonality: the next 20 trading days

Over the next 20 trading days from Oct 10, AnaptysBio averaged +5.2% across the last 5 years, rising in 3 of them.

Next 20 trading days, by year

+31.7%2021+13.0%2022−15.7%2023−32.8%2024+26.4%2025

Average move and hit rate

WindowAverageYears higher
Next 5 trading days+4.5%3 of 5
Next 10 trading days+4.0%4 of 5
Next 15 trading days−1.0%3 of 5
Next 20 trading days+5.2%3 of 5
Next 30 trading days−4.7%3 of 5

For scale, ANAB’s typical 20-trading-day move in either direction is about 11.1%.

AnaptysBio market cap and key statistics

AnaptysBio’s market cap is $1.36B and revenue of $106.1M over the last twelve months.

Valuation

Market cap
$1.36B
Forward P/E
21
EPS, TTM
−$0.96
Gekko Fair Value
$66.63

Trading

Volume
371,592
Avg volume, 20 days
592,633
52-week high
$72.36
52-week low
$30.27
Shares outstanding
29.90M

Financials

Revenue, TTM
$106.1M
Profit margin
247%
Return on equity
-114.5%
Quarterly earnings growth, YoY
0.0%

Risk and income

Beta
0.45
Typical daily move
±4.4%
Typical 20-day move
±11.1%

AnaptysBio stock news this week

Coverage of AnaptysBio this week reads positive: 3 positive, 0 neutral and 1 negative headlines.

News sentiment positive

AnaptysBio peers

AnaptysBio’s 6 largest industry peers by market value, with today’s move, GekkoIndex zone and gap to Gekko Fair Value.

StockTodayGekkoIndex zonevs Fair Value
AMGNAmgen+0.4%Neutral25.5% below
GILDGilead Sciences−0.9%Neutral4.2% above
MRNAModerna−4.8%Neutral62.7% above
NTRANatera−1.0%Neutral10.3% above
IQVIQVIA+0.8%Neutral8.4% above
UTHRUnited Therapeutics−0.6%Neutral14.4% below

A peer links to its own page where one exists.

In the Buying zone today

Reporting earnings this week

Popular on Gekko

AnaptysBio stock FAQ

What is AnaptysBio’s market cap?

AnaptysBio’s market cap is $1.36B at the Oct 12, 2026 close of $46.04, with 29.90M shares outstanding.

What is the AnaptysBio stock forecast?

The consensus analyst 12-month price target for AnaptysBio is $87.25, +89.5% from the last close. Of the 7 firms that rated the stock in the last 90 days, 7 rate it a buy, 0 a hold and 0 a sell. Gekko doesn’t publish price predictions of its own.

Is AnaptysBio stock overvalued or undervalued?

On Gekko’s estimate AnaptysBio is undervalued: the Oct 12, 2026 close of $46.04 is 30.9% below Gekko Fair Value of $66.63. Gekko Fair Value is recalculated every trading day, and a gap inside 5% either way counts as about fair value.

When does AnaptysBio report earnings next?

AnaptysBio is expected to report on Nov 3, 2026, after the market closes (22 days away). Analysts expect earnings of −$1.84 per share on revenue of $25.56M. AnaptysBio beat the earnings estimate in 6 of its last 8 reports, moving 5.5% on average across the report.

What is AnaptysBio’s 52-week high and low?

AnaptysBio’s 52-week high is $72.36 and its 52-week low is $30.27; it closed at $46.04 on Oct 12, 2026, +44.9% over the past year.

Is AnaptysBio stock a buy right now?

Gekko describes the data; it does not make buy or sell recommendations. On the swing-trade checklist, 3 of the 5 items with data read as supportive (gekkoindex, fair value and seasonality) and 2 as headwinds (trend and earnings risk). The checklist is a description of current data, not a recommendation.

How this page works

During US trading hours the price at the top of the page is a delayed quote, refreshed every 15 minutes; everything else is rebuilt after each US market close. The GekkoIndex, Gekko Fair Value and the checklist are Gekko’s own, and the Gekko Brief is written by AI from this page’s data and checked against it before it is published. How Gekko’s data works →

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