Mesoblast (MESO) Stock Analysis & Forecast

Oct 12 close

$14.27−0.02 (−0.1%)

Gekko Brief

AI summaryOct 12 close

Mesoblast draws attention this week after reporting RYONCIL net product sales of $115 million for fiscal year 2026, up from $17 million in fiscal year 2025, with total revenue of $120 million for the year. Commentary from Bell Potter frames the stock constructively, citing attractive short-term revenue growth and pivotal clinical events ahead, while separate coverage notes the company has completed patient treatment in its pivotal chronic low back pain trial for rexlemestrocel-L, with top-line results expected around mid-next year, alongside efforts to expand RYONCIL into a broader franchise for adult patients.

MESO closed at $14.27, down 0.1%, sitting below both its 50-day average of $15.73 and its 200-day average of $15.80, with the 50-day below the 200-day. The GekkoIndex reads 61.6, placing the stock in the Accumulation zone. Price sits 37.1% below Gekko Fair Value of $22.69.

No confirmed earnings date appears on the calendar for the next 20 trading days, and no insider, Congress or unusual options activity shows up in the respective 90-day and 30-day windows. Seasonality over this stretch has averaged a 1.8% decline across 5 years, rising in 2 of them, a headwind worth noting given the stock's recent weakness. Separately, consensus from 2 covering analysts, both rated buy, carries a target of $37, implying upside of 159.3% from current levels.

Written by AI from the Oct 12, 2026 close and checked automatically against the figures on this page.

Mesoblast price vs fair value

$22.69$14.27Oct ’25Apr ’26Oct ’26
Close $14.27200-day averageGekko Fair Value $22.69

Mesoblast quick facts

Market cap
$1.85B
P/E ratio
—
Forward P/E
454.6
EPS, TTM
−$0.44
Revenue, TTM
$120.3M
Profit margin
-47.8%
Dividend yield
—
Beta
0.86
Volume
143,760 avg 219,406
1-year return
−26.9%
Typical daily move
±3.3%
Typical 20-day move
±10.8%
50-day average
$15.73
200-day average
$15.80
Next earnings
—
Shares outstanding
129.9M
52-week range
$13.05$21.50

Mesoblast swing-trade checklist

Mesoblast scores 2 supportive, 0 mixed and 2 headwinds across the 4 checklist items with data.

Six things swing traders check before a 20-day hold, read from the latest data.

2 supportive0 mixed2 headwinds

  • Trendheadwind

    Below 50 and 200-day

    Close $14.27 is below the 50-day ($15.73) and 200-day ($15.80) averages, and the 50-day is below the 200-day.

    See the chart
  • GekkoIndexsupportive

    61.6, Accumulation

    Reading 61.6 is in the Accumulation zone.

    See the GekkoIndex
  • Fair valuesupportive

    37.1% below

    Price is 37.1% below Gekko Fair Value (more than 5% below).

    See fair value
  • Smart moneyno data

    No data

    No insider, Congress or unusual options activity in the window.

    See smart money
  • Earnings riskno data

    No data

    No confirmed report date on the calendar.

    See earnings
  • Seasonalityheadwind

    −1.8% on average

    From this point in the calendar, the next 20 trading days averaged −1.8% over 5 years, rising in 2 of them.

    See seasonality

A description of current data, not a recommendation. How this page works

Mesoblast stock chart and price history

Mesoblast closed at $14.27 on Oct 12, 2026, −26.9% over the past year, inside a 52-week range of $13.05 to $21.50.

Close50-day average200-day averageVolume
Mesoblast share price, past year, with 50-day and 200-day moving averages and volume$16$18$20NovDecJan 2026FebMarAprMayJunJulAugSepOct14.27

Use the left and right arrow keys to read daily values.

Performance Breakdown

1 month
−7.8%
3 months
−14.8%
6 months
−2.9%
1 year
−26.9%
The full MESO chart adds GekkoIndex, insider, options, Congress and hedge fund markers, plus TrendCandles™.Open MESO in Gekko

Follow Mesoblast through every session

Put MESO on a Gekko watchlist and see its GekkoIndex, Gekko Fair Value and smart money signals update on the chart as they change.

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About Mesoblast

Mesoblast works on allogeneic cell-based therapies, meaning treatments built from donor-derived cells rather than a patient's own. It targets a wide range of conditions, among them heart disease, spinal and orthopedic disorders, cancer, blood disorders, and immune and inflammatory illnesses. Its work centers on a regenerative medicine platform built around specialized mesenchymal lineage cells, with several candidates now in Phase III trials, including remestemcel-L for severe graft versus host disease and COVID-related respiratory distress, rexlemestrocel-L for advanced chronic heart failure, and MPC-06-ID for chronic low back pain linked to degenerative disc disease. Another program, MPC-300-IV, is being studied for rheumatoid arthritis that has not responded to biologic treatment and for diabetic kidney disease.

To move these programs forward and reach markets, Mesoblast has formed partnerships with other companies. Tasly Pharmaceutical Group distributes two of its heart-related therapies in China, JCR Pharmaceuticals works with it on treatments for wound healing in epidermolysis bullosa, and Grünenthal collaborates on cell therapy for chronic low back pain.

Mesoblast was founded in 2004 and is headquartered in Melbourne, Australia, with operations also reaching the United States, Singapore, the United Kingdom, and Switzerland. Its shares trade under the ticker MESO.

Sector
Health technology
Website
mesoblast.com

Mesoblast GekkoIndex: the smart money zone

Mesoblast’s GekkoIndex — Gekko’s 0 to 100 smart money score — reads 61.6, in the Accumulation zone, down 4.3 points over five sessions.

010061.6Accumulation

Down 4.3 points over five sessions.

Reading for Oct 12, 2026

What followed past readings in each zone

ZoneReadings5 days10 days20 days50 days
Buying15+3.6%+3.8%−1.4%−0.5%
Accumulation (current zone)207+1.0%+3.0%+6.3%+11.9%
Neutral376+1.6%+2.8%+5.5%+13.7%
Distribution33+12.2%+8.8%+8.5%+15.3%
Selling2Too few readings yet

Average MESO share-price change over the trading days after each daily reading in its GekkoIndex history. Across every stock Gekko tracks, Accumulation readings averaged +2.2% over 20 days. Past behaviour doesn’t guarantee future results.

Accumulation zone: Institutional interest building. About the five zones →

See every daily GekkoIndex reading plotted over the MESO price, zone by zone.Track MESO in Gekko

Is Mesoblast stock overvalued? Gekko Fair Value

Mesoblast trades 37.1% below Gekko Fair Value of $22.69, so the shares are undervalued on Gekko’s estimate.

Gekko’s own estimate of what Mesoblast shares are worth, recalculated every trading day.

$22.69

Gekko Fair Value, Oct 10, 2026

37.1% Undervalued

At the end of Aug 2026 the price was 43.3% below the estimate.

Gekko Fair ValueShare price, month end
$23$14Aug 2026SepOct 2026

How Gekko Fair Value works →

Gekko Fair Value on every chart, with the gap to price updating daily.Open MESO in Gekko

Mesoblast insider and Congress trading

No open-market insider purchases were filed for Mesoblast, and no Congress trades were disclosed, in the last 90 days.

Plus buybacks, unusual options and fund positions, each dated to when it became public.

Insider buying last 90 days

No open-market insider purchases were filed for MESO in the last 90 days.

From Form 4 filings, dated to when each was filed.

Every MESO insider filing, plotted on the chart in Gekko.Open MESO in Gekko

Congress trades last 90 days

No trades in MESO were disclosed by members of Congress in the last 90 days.

From congressional disclosures, which report amounts as ranges.

Congress disclosures for MESO, plotted on the chart in Gekko.Open MESO in Gekko

Mesoblast earnings: next date and track record

Mesoblast beat the EPS estimate in 4 of its last 8 reports, moving 5% on average across the report.

4 of 8reports beat the EPS estimate
±5%average move across the report
4 of 8reports followed by a gain

Share-price move across each report

−3.2%Feb ’25+0.3%Apr ’25−2.0%Jul ’25−14.2%Aug ’25+7.3%Nov ’25−6.3%Feb ’26+1.2%Apr ’26+5.8%Aug ’26

Last earnings call, Aug 26, 2026 AI summary

What they said
Mesoblast reported RYONCIL net revenues of $115 million for fiscal year 2026, its first full year post-launch, establishing it as the only FDA-approved allogeneic mesenchymal stromal cell product. The company holds 1,100+ patents with protection beyond 2044. Revenue is being reinvested into Phase 3 programs targeting chronic low back pain and inflammatory heart failure, with total addressable markets exceeding $20 billion. Label expansion targets include adult GvHD (3x larger than pediatric market) and Duchenne muscular dystrophy.
Guidance
Management is pursuing RYONCIL label expansion into adult GvHD, Duchenne, and other rare inflammatory conditions. Phase 3 blockbuster programs in chronic low back pain and inflammatory heart failure represent markets exceeding $20 billion combined. No specific revenue or EPS targets were provided in this excerpt.
ReportedEPSSurpriseRevenueSurpriseMove
Aug 26, 2026−$0.13
est −$0.11
−23.2%$68.95M
est $53.87M
+28.0%+5.8%
Apr 30, 2026−$0.07
est −$0.08
+11.7%$34.45M
est $29.20M
+18.0%+1.2%
Feb 26, 2026−$0.31
est −$0.24
−31.2%$51.34M
est $53.06M
−3.2%−6.3%
Nov 26, 2025−$0.07
est −$0.10
+30.0%——+7.3%
Aug 28, 2025−$0.32
est −$0.20
−60.0%$15.58M
est $14.13M
+10.2%−14.2%
Jul 29, 2025−$0.43
est −$0.37
−15.2%$14.02M
est $14.13M
−0.8%−2.0%
Apr 30, 2025−$0.21
est −$0.35
+38.3%$7.02M
est $7.48M
−6.2%+0.3%
Feb 26, 2025−$0.04
est −$0.41
+90.2%$1.58M
est $7.48M
−78.9%−3.2%

“Move” is the close of the first session after the report compared with the close of the last session before it, so it reads the same whether the company reported before the open or after the close.

Mesoblast stock forecast and analyst price targets

Analysts’ average 12-month price target for Mesoblast is $37.00, +159.3% from the last close, from 2 firms rating the stock in the last 90 days.

$37.00consensus 12-month target, +159.3% from the last close
Low $35High $39
Buy2
Hold0
Sell0

Each firm’s latest rating in the last 90 days: 2 firms.

Latest analyst actions

DateFirmRatingTargetvs price
Sep 3Maxim GroupBuy, maintained$35+145.3%
Aug 27Piper SandlerBuy, reiterated$39+173.3%
+6.3%average 20-day move after past Accumulation readings
−1.8%average move over the next 20 trading days in the last 5 years
±3.3%typical daily move, from the 14-day average range

Gekko doesn’t publish price predictions. These are analyst targets and historical base rates, which don’t guarantee future results.

Mesoblast seasonality: the next 20 trading days

Over the next 20 trading days from Oct 10, Mesoblast averaged −1.8% across the last 5 years, rising in 2 of them.

Next 20 trading days, by year

+14.3%2021−8.0%2022+9.9%2023−7.4%2024−20.3%2025

Average move and hit rate

WindowAverageYears higher
Next 5 trading days−1.0%2 of 5
Next 10 trading days−0.1%2 of 5
Next 15 trading days−2.7%2 of 5
Next 20 trading days−1.8%2 of 5
Next 30 trading days+1.8%2 of 5

For scale, MESO’s typical 20-trading-day move in either direction is about 10.8%.

Mesoblast market cap and key statistics

Mesoblast’s market cap is $1.85B and revenue of $120.3M over the last twelve months.

Valuation

Market cap
$1.85B
Forward P/E
454.6
EPS, TTM
−$0.44
Gekko Fair Value
$22.69

Trading

Volume
143,760
Avg volume, 20 days
219,406
52-week high
$21.50
52-week low
$13.05
Shares outstanding
129.9M

Financials

Revenue, TTM
$120.3M
Profit margin
-47.8%
Return on equity
-9.9%
Quarterly earnings growth, YoY
0.0%

Risk and income

Beta
0.86
Typical daily move
±3.3%
Typical 20-day move
±10.8%

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Mesoblast stock FAQ

What is Mesoblast’s market cap?

Mesoblast’s market cap is $1.85B at the Oct 12, 2026 close of $14.27, with 129.9M shares outstanding.

What is the Mesoblast stock forecast?

The consensus analyst 12-month price target for Mesoblast is $37.00, +159.3% from the last close. Of the 2 firms that rated the stock in the last 90 days, 2 rate it a buy, 0 a hold and 0 a sell. Gekko doesn’t publish price predictions of its own.

Is Mesoblast stock overvalued or undervalued?

On Gekko’s estimate Mesoblast is undervalued: the Oct 12, 2026 close of $14.27 is 37.1% below Gekko Fair Value of $22.69. Gekko Fair Value is recalculated every trading day, and a gap inside 5% either way counts as about fair value.

What is Mesoblast’s 52-week high and low?

Mesoblast’s 52-week high is $21.50 and its 52-week low is $13.05; it closed at $14.27 on Oct 12, 2026, −26.9% over the past year. Over the last five years the shares peaked at $22.00 on Dec 30, 2024.

Is Mesoblast stock a buy right now?

Gekko describes the data; it does not make buy or sell recommendations. On the swing-trade checklist, 2 of the 4 items with data read as supportive (gekkoindex and fair value) and 2 as headwinds (trend and seasonality). The checklist is a description of current data, not a recommendation.

How this page works

During US trading hours the price at the top of the page is a delayed quote, refreshed every 15 minutes; everything else is rebuilt after each US market close. The GekkoIndex, Gekko Fair Value and the checklist are Gekko’s own, and the Gekko Brief is written by AI from this page’s data and checked against it before it is published. How Gekko’s data works →

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